Serving the Lowcountry and Coastal Empire of Georgia and South Carolina.

Douglas Gresham, M.D.

Douglas Gresham, M.D.




Board Certification:

Internal Medicine; Endocrinology


Endocrinology and Metabolism, Lahey Clinic Medical Center/Joslin Clinic, Burlington and Boston, Mass.

Academic Appointment:

Clinical Fellow, Harvard Medical School, Boston Mass.


Intern in Medicine and Resident in Medicine, New England Deaconess/Beth Israel Hospital, Boston, Mass.


Doctor of Medicine, University of Massachusetts Medical School, Worcester, Mass.


Fellow of the American Association of Clinical Endocrinology

Hospital Affiliations:

St. Joseph's / Candler
4.8 out of 5
221 Patient Ratings


Dr. Douglas Gresham has been a cornerstone of the Savannah healthcare landscape since 1984. Board certified in internal medicine and endocrinology, Dr. Gresham operated his own private practice for 37 years before joining forces with SouthCoast Health. With business responsibilities no longer an issue, Dr. Gresham has the opportunity to focus on his passion: improving the lives of patients.

Patient care, along with a love for science and problem solving, led Dr. Gresham to begin his medical career in the late 1970s. It was during medical school when he first became attracted to endocrinology, which focuses on diagnosing, treating, and managing endocrine disorders or those affecting the body's secretion of hormones such as thyroid problems or diabetes.

“I just love to sit down with patients and discuss their problems, teach them what I can about the problems, and outline a treatment plan that will help them the most,” Dr. Gresham says. “Making a plan and seeing it come to fruition is still an incredible part of my job.” 

Dr. Gresham enhances and builds upon decades of knowledge and experience by reading medical journals, brainstorming with colleagues, and periodically attending national meetings. A fellow of the American Association of Clinical Endocrinology, Dr. Gresham has co-authored approximately a dozen papers in the field of organic chemistry and endocrinology.   

Helping patients with thyroid disease return to normalcy with minimal problems remains a satisfying aspect of his work. However, treating pregnant diabetic women arguably has the biggest impact on him as a physician.

“For pregnant women, Type 1 diabetes can be particularly challenging,” he explains, “and the baby’s safety can be in jeopardy. That’s when I come in, work with the patient every week, and get their diabetes under control. And before you know it, they give birth to a normal, healthy baby. I’ve had many of those experiences through the years, and it’s probably the greatest reward I see.”

In his spare time, Dr. Gresham enjoys tinkering with vintage cars. He and his wife Elise, a registered nurse, have three grown children. One child is a neurology nurse practitioner, another works in the House Committee on Oversight and Reform, and their third is a computer software engineer. 

Patient Reviews

April, 2023

Very Good !! Excellent Doctor.

April, 2023

Excellent, competent care based in a deep understanding of and abikity to apply endocrine science to my clinical presentation. Excellent experience.

April, 2023

Keisha in Dr. Gresham's office was so kind, knowledgeable, professional, helpful, and friendly. Dr. Gresham was as he always is... calm, and caring and knowledge.

February, 2023

Very, very good. keep up the great works, God Bless you all thank

December, 2022

This was my first visit with Dr Gresham. What a kind and caring Dr he is!! It?s a great experience to actually sit beside a Dr who isn?t looking into a computer as we speak. He took his time to listen and that says a lot!! Old school is a great thing!

December, 2022

Dr Gresham and his asst were attentive and understanding when a highway accident made me late for my appt. Lab services were also prompt and efficient

December, 2022

Extremely well run practice Rare these days

December, 2022

My visit with Southcoast Health was a very good experience. Dr. Gresham was not only friendly and patient, but he actually sat down with me and took the time to explain my current health issue. The front desk and lab staff were courteous and friendly as well. Thanks!!

November, 2022

I enjoyed my visitation and my doctor listened through dialogue while considering my views on my health.

November, 2022

The front desk Check in staff was very nice and professional. Dr Greshams nurses were wonderful. Dr Gresham was very knowledgeable about my moms condition and what changes we needed to make for a better outcome. Hes the best!

November, 2022

Good service so.far . The nurse keisha was Very nice..also the doctor have been. Given me good advice. Has .a good provider.

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