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Serving the Lowcountry and Coastal Empire of Georgia and South Carolina.

Leslie Sizemore, M.D.

Leslie Sizemore, M.D.


Primary Care, Family Medicine


Board Certification:

American Board of Family Medicine


Family Medicine, University Hospital and Clinics, Lafayette, Louisiana

Medical School:

Doctor of Medicine, Xavier University School of Medicine, Oranjestad, Aruba


American Academy of Family Physicians

Hospital Affiliations:

St. Joseph's/Candler; Memorial Health University Medical Center
4.6 out of 5
987 Patient Ratings



Dr. Leslie Sizemore has a broad vision and perspective of medicine. That, she says, drew her to primary care.


“I’ve never pigeonholed myself into one specific thing,” she explains. “I’ve always wanted to treat all ages, the whole body, and the whole person.” 

Having spent her formative years on St. Simons Island, Dr. Sizemore has a personal connection with the Coastal Empire. She pairs that with her continuing desire to forge a bond with her patients through medicine. 

“In primary care, it’s all about the relationships you have with your patients,” she says, “and those relationships can be lifelong. And I love developing that rapport.”

Dr. Sizemore’s wide scope of care extends beyond “writing prescriptions.” In the past, this has involved reconnecting family members with an ailing relative and helping a patient and their family find the right hospice facility.

“Whether it’s through treatment or compassion, improving a patient’s quality of life is the most rewarding part of my job.”  

According to Dr. Sizemore, the sweeping age range of her primary care clients keeps things interesting. Treating patients ages 4 and older means dealing with an array of ailments such as the common cold, urological issues, assistance with healthy aging, and more.

Primary care also allows her to provide women’s health services. 

“When it comes to women’s health,” Dr. Sizemore says, “many females prefer visiting a female physician. I’m grateful to provide those services for ladies. And I can treat the whole family, too. I don’t feel limited in what I’m able to do for my patients.”

Being able to treat such a wide range of patients and medical issues requires a breadth of medical knowledge. Dr. Sizemore stays on top of the latest data by reading as many medical journals as possible. In addition, she attends American Academy of Family Physicians conferences on both the state and national level, which helps her remain in tune with breaking developments, new treatments, and contemporary best practices. 

“I enjoy staying on my toes,” she explains. “We’re perpetual students, because primary care medicine is constantly changing. I try to be the best physician I can be by always striving to learn something new.” 

As part of a SouthCoast Health family care practice, Dr. Sizemore works alongside other physicians, sharing her professional opinion with and receiving insight from her colleagues.

“We can bounce ideas off of each other and discuss different medical scenarios,” she says. 

When a case calls for a physician outside of the primary care wheelhouse, Dr. Sizemore says she and her contemporaries have SouthCoast Health specialists “at our fingertips.”

Outside of the office, Dr. Sizemore enjoys spending time with her son and stepson, going on family golf outings, cooking, and dining out with her husband. 

Patient Reviews

April, 2022

This was my first visit and I am glad I made the choice to switch to South Coast Health

April, 2022

New to clinic and felt welcomed!

April, 2022

Dr. Sizemore is the best!!

April, 2022

Dr. Sizemore is awesome!!

April, 2022

Service was wonderful

March, 2022

Professional caring staff

March, 2022

It?s a beautiful office and staff is very friendly. Dr. Seizmore was very through and on time. Overall experience was good.

March, 2022

Dr. Sizemore was very helpful and caring.

December, 2021

The best doctor I have ever met. The staff was pleasant, courteous, professional, and caring.

November, 2021

I visit Dr. Sizemore every 3 months for a medicine checkup and I can honestly say she is the best Primary Care Doctor I have ever seen. She is always caring, listens to any and all medical concerns I may have, and always takes the time to listen to whatever concerns I may have. Additionally, Dr. Sizemore?s nurses Greg and Beth are equally excellent as they always treat me with kindness and truly care about my overall health. Finally, if I ever need anything, I receive a response in less than 24 hours. This is the best medical practice I have ever been to and I will remain a patient here for life!!

November, 2021

I would drive across the state to see Dr. Sizemore. One of the most caring and thorough doctors I have ever been a patient of. Ten out of ten experience!

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